Immunomodulator effects of lactoferrin in Rats immunized with the Rev1 Vaccine

Abstract

Lactoferrin has many medical effects such as anti-microbial, anti-inflammatory and antioxidant. The current study was designed to investigate the immunomodulatory effect lactoferrin For this purpose lactoferrin and Rev1vaccine had been given to three animal experimental (rats) groups,  while the fourth group served as the control negative group.

The results of the current study showed that total leukocytic count and immune markers (IL6, IL12 and TNFα) significant increases in 14 and 21 days after immunization in the 1^st, the 2^nd and 3^rd groups. The study concluded lactoferrin and Rev1 vaccine have a synergistic effect when they are given in the same group.