The effect of extracted exopigments of pseudomonas aeroginosa on different microorganisms : an invetro study

Abstract

Pseudomonas aeruginosa is gram-negative Bacteria are among the most important pathogenic agents in both human and veterinary medicine, responsible for a wide range of diseases affecting humans and animals. These include wound and burn infections, eye and skin infections, urinary tract infections, otitis media, septicemia, and infections of bones and joints. Otitis media, in particular, is a frequently encountered condition in domestic animals such as cats and dogs. In order to isolate and identify Pseudomonas aeruginosa strains capable of producing pyocyanin and to assess their antibiotic resistance, a total of 120 ear swabs were obtained from domestic cats clinically diagnosed with otitis media. These samples were collected from cats presented to private veterinary clinics in Tikrit City from December 2024 to march 2025, using sterile cotton swabs.The isolated P. aeruginosa strains showed a high capability to produce the extracellular pigment pyocyanin, and they exhibited resistance to a wide range of antibiotics compared to Staphylococcus aureus, Enterococcus faecalis, and Escherichia coli, which were found to be sensitive to antibiotics. In contrast, the isolated P. aeruginosa strains were resistant to antifungal agents, unlike Candida albicans, which was sensitive to the antifungal drug.