Immunohistochemical of Glycoprotein Cluster of Differentiation 44 (CD44) Expression in Breast Cancer

Authors

  • Entedhar Rifaat Sarhat Department of Biochemistry, Faculty of Medicine, University of Tikrit, Iraq Author
  • Zubaida N.M Albarzanji Department of Basic science, Faculty of Dentistry, University of Kirkuk, Iraq Author
  • Siham Agmee Wadee Department of Physiology, Pharmacology and Biochemistry ,Collage of Veterinary Medicine, University of Tikrit Author
  • Nawar J. Ali Department of pathology and poultry disease, Collage of Veterinary Medicine, University of Tikrit. Author

DOI:

https://doi.org/10.25130/tjvs.3.1.12

Keywords:

CD44s; Breast cancer; Immunohistochemical staining

Abstract

Breast cancer (BC) is the most frequently diagnosed cancer in women worldwide, and it is ranked as second in terms of cancer related death in women. The aim of this study several stem markers have been described for the various histological subtypes of breast cancer, stem cells (CSCs) of breast cancer have been found to strongly express adhesion molecule glycoprotein cluster of differentiation 44  (CD44). CD44  is expressed in the membrane of the cells, so it differs from the other studied markers which were cytoplasmic expressed markers. Negative expression scored (0) were observed in 15 out of 31samples (48.3%), while score (+) found in 5 out of 31samples (16.12%), score (++) found in 2 out of 31samples (6.4%)and score (+++) found in 9 out of 31samples.

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Published

2024-06-01

Issue

Vol. 3 No. 1 (2024)

Section

Articles

How to Cite

Immunohistochemical of Glycoprotein Cluster of Differentiation 44 (CD44) Expression in Breast Cancer. (2024). Tikrit Journal of Veterinary Science, 3(1), 140-148. https://doi.org/10.25130/tjvs.3.1.12